KMID : 0368820070460050499
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Journal of the Korean Neuropsychiatr Association 2007 Volume.46 No. 5 p.499 ~ p.506
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Perseverative Pattern of Decision-Making in Alcohol Dependent Patients
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Kim Nam-Wook
Ku Jeong-Hun Lee Eun Jung Young-Chul Choi You-Kung
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Abstract
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Objectives: The relationship between substance dependence and poor decision making has received much attention in recent years. This study aimed to test the hypothesis that alcohol dependent subjects would demonstrate a more perseverative decision-making pattern, during ambiguous situations.
Methods: 15 alcohol dependent patients and 15 healthy normal controls performed a novel computerized decision-making task, which presented figures of coins. The subjects were instructed to guess whether the total number of coins was ¡¯odd¡¯ or ¡¯even¡¯. Besides these two response, one could select a third alternative - ¡¯pass¡¯ - in case the chances were assumed to be low.
Results: There was significant difference in performance between the two groups (F=4.339, p=0.008). The control group gained 15.4+/-14.4 points, whereas the alcohol dependent group lost 0.6+/-5.3 points. The normal control group demonstrated a tendency to make more pass responses as the trials were repeated. In contrast, the alcohol dependent group didn¡¯t make use of the alternative, but kept challenging between ¡¯odd¡¯ and ¡¯even¡¯, although they sensed that the chances were low.
Conclusion: The alcohol dependent patients demonstrated a more rigid and perseverative response pattern and showed deficits in making use of compromise alternatives.
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KEYWORD
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Decision making, Alcohol dependence, Perseverative responses
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